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Aortic and biventricular function in pediatric meningococcal septic shock survivors as assessed with MRI

✍ Scribed by Heynric Grotenhuis; Hennie Knoester; Jos J Westenberg; Lucia JM Kroft; Albert de Roos


Publisher
BioMed Central
Year
2012
Tongue
English
Weight
85 KB
Volume
14
Category
Article
ISSN
1097-6647

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✦ Synopsis


Septic shock is one of the major causes of death in children and is characterized by a massive inflammatory response. To present date, no studies have been performed to assess the impact of such an 'inflammatory hit' on aortic wall structure and myocardial performance.

This study shows that despite adequately preserved systolic biventricular function, frequently reduced aortic elasticity may indicate aortic wall pathology, being associated with biventricular hypertrophy and concomitant delayed biventricular relaxation in pediatric patients after septic shock.