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Anxiolytic-like effects induced by nitric oxide synthase inhibitors microinjected into the medial amygdala of rats

✍ Scribed by Daniel Forestiero; Carlos Mora Manfrim; Francisco Silveira Guimarães; Rúbia Maria Weffort de Oliveira

Publisher: Springer
Year: 2005
Tongue: English
Weight: 207 KB
Volume: 184
Category: Article
ISSN: 0033-3158
DOI: 10.1007/s00213-005-0270-6

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re