𝔖 Bobbio Scriptorium
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Antiviral activity of colostrum and serum immunoglobulins a and g

✍ Scribed by E.L. Palmer; G.W. Gary Jr.; R. Black; M.L. Martin

Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
376 KB
Volume
5
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

Enteric virus‐specific IgA and IgG present in paired human sera and colostrums were measured by the enzyme‐linked immunosorbent assay (ELISA). Virus‐specific IgA was present in all colostrums, but virus‐specific IgG could not be detected. The reverse was true when sera were assayed. Most of these colostrums also neutralized either polio virus or reovirus, as did IgA, which was separated from a pool of colostrums by exclusion chromatography. No correlation could be made between levels of neutralizing and ELISA antibody titers in colostrums.

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Serum immunoglobulins and the activity of natural killer (NK) cells of 50 epileptic patients (eight with idiopathic generalized epilepsy and 42 with cryptogenic partial epilepsy) and 28 controls have been studied. The values of IgA, IgG and IgM were the same in patients and controls. The NK activity