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Antitumor Sesquiterpenes from Euonymus nanoides

✍ Scribed by Hong Wang; Xuan Tian; Yuanjiang Pan

Publisher
John Wiley and Sons
Year
2003
Tongue
German
Weight
93 KB
Volume
86
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

The isolation, structure elucidation, and antitumor activity of four new sesquiterpene polyol esters, i.e., of 6__α__,13‐bis(acetyloxy)‐9__β__‐(cinnamoyloxy)‐1__β__‐(furan‐3‐ylcarbonyl)oxy]‐4__α__‐hydroxy‐β‐dihydroagarofuran (1), 13‐(acetyloxy)‐9__β__‐(benzoyloxy)‐4__α__‐hydroxy‐1__β__,6__α__‐bis[(2‐methylbutanoyl)oxy]‐β‐dihydroagarofuran (2), 1__β__,6__α__,13‐ tri(acetyloxy)‐9__β__‐(cinnamoyloxy)‐4__α__‐hydroxy‐β‐dihydroagarofuran (3), and 6__α__,13‐bis(acetyloxy)‐9__β__‐(benzoyloxy)‐4__α__‐hydroxy‐1__β__‐[(2‐methylbutanoyl)oxy]‐β‐dihydroagarofuran (4), and of five known sesquiterpene polyol esters 5–9 from the seed oil of Euonymus nanoides Loes. are reported (β‐dihydroagarofuran=octahydro‐2,2,5a,9‐tetramethyl‐2__H__‐3,9a‐methano‐1‐benzoxepin).

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