Antitumor effects of fusions composed of dendritic cells and fibroblasts transfected with genomic DNA from tumor cells
โ Scribed by Motoyuki Nakamura; Tetsuro Kikuchi; Donald W. Kufe; Tsuneya Ohno
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 244 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0340-7004
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High-molecular-weight genomic DNA isolated from a human cutaneous squamous cell carcinoma (AS) was assayed for its ability to induce tumorigenic transformation of NIH 3T3 cells. Subcutaneous injection of NIH 3T3 cells cotransfected with DNAs from AS tumor and pSV2-neo plasmid not only induced tumors