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Antitumor effect of methionine-depleting total parenteral nutrition with doxorubicin administration on yoshida sarcoma-bearing rats

✍ Scribed by Narihide Goseki; Sigeru Yamazaki; Mitsuo Endo; Tokio Onodera; Goro Kosaki; Yutaka Hibino; Tokuo Kuwahata

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 656 KB
Volume: 69
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19920401)69:7<1865::aid-cncr2820690732>3.0.co;2-m

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Background. Previous studies have shown that a methionine-lacking diet inhibited tumor growth in rats. The aim of this study was to determine how methionine free total parenteral nutrition (MTPN) can result in the inhibition of tumor growth on tumor protein metabolism in rats. Methods. On day 0, AH