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Antitumor effect of levamisole in combination with anaerobic corynebacterium, OK-432 (streptococcal preparation), and chemotherapy in mice

โœ Scribed by Shisei Yamagata; Tetsuji Koh; Mitsutoshi Oride; Takao Hattori


Publisher
Springer-Verlag
Year
1980
Tongue
English
Weight
301 KB
Volume
7
Category
Article
ISSN
0340-7004

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The natural-killer(NK)-cell-mediated cytotoxicity to syngeneic tumor cells can be augmented by in vivo priming and subsequent in vitro challenge with the streptococcal preparation OK432. Supernatants of cocultures of spleen cells with OK432 contained interleukin-2 (IL-2) and interferon (IFN), mainly