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Antitumor Activity of the Antimicrobial Peptide Magainin II against Bladder Cancer Cell Lines

✍ Scribed by Jan Lehmann; Margitta Retz; Sukhvinder S. Sidhu; Henrik Suttmann; Michael Sell; Friedrich Paulsen; Jürgen Harder; Gerhard Unteregger; Michael Stöckle


Book ID
113609175
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
328 KB
Volume
50
Category
Article
ISSN
0302-2838

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## Abstract A pharmacodynamic study of cisplatin (DDP) was conducted using the gastric cancer cell lines MKN‐45 and MKN‐74 in vitro. Ten thousand tumor cells were incubated with 0.4–500 μg/ml DDP for 1–25 h, followed by recovery culture for a further 48 h. At the end of incubation, cell viability w