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Antitumor activity of platinum(II) complexes with histamine and radioiodinated histamine in a transplantable murine adenocarcinoma model

✍ Scribed by Piotr Garnuszek; Urszula Karczmarczyk; Michał Maurin


Book ID
116799220
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
325 KB
Volume
35
Category
Article
ISSN
0969-8051

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Mechanistic information on the reaction
✍ M. Shoukry; H. Hohmann; R. van Eldik 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 572 KB

The reaction of Pd(Me,en)Cl, (Me,en =N,N,iV',N'-tetramethylethylenediamine) with inosine and 5'-inosine monophosphate was studied as a function of chloride concentration and pH. Evidence for the formation of a 1:l complex with these nucleophiles is presented, and the kinetic data indicate that Pd(Me