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Antitumor activity of interleukin 12 against interleukin 2-transduced mouse glioma cells

โœ Scribed by Tetsuro Kikuchi; Tatsuhiro Joki; Yasuharu Akasaki; Toshiaki Abe; Tsuneya Ohno


Book ID
117469248
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
190 KB
Volume
135
Category
Article
ISSN
0304-3835

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Interleukin 12 (IL-12) exhibits anti-tumor activity in a variety of laboratory models. Although IL-12 itself activates strong anti-tumor activity, the combination of vaccine therapy with IL-2-transduced tumor cells and systemic rIL-12 has been shown to cure tumor-bearing mice more effectively than e