Background: Paclitaxel (BMS-181339: Taxol) is a promising agent against previously treated breast cancer. The antitumor activity of paclitaxel was evaluated using five human breast carcinoma xenografts in nude mice. Methods: Paclitaxel at 20 mg/kg dissolved in 0.2 ml ethanol/cremophor EL solution wa
โฆ LIBER โฆ
Antitumor Activity and Pharmacokinetics of a Morpholino-anthracycline Derivative (KRN8602) against Human Breast Carcinoma Xenografts Serially Transplanted into Nude Mice
โ Scribed by Kubota, Tetsuro ;Suto, Akihiko ;Josui, Kazuya ;Ishibiki, Kyuya ;Abe, Osahiko ;Yamada, Yoshinori ;Asanuma, Fumiki ;Kawamura, Eiji ;Koh, Jun-ichi ;Shiina, Eiichi ;Inada, Takao ;Ogata, Yoshiro
- Book ID
- 108579134
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1990
- Tongue
- English
- Weight
- 390 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0910-5050
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The effect of experimental cancer chemotherapy with mitomycin C (MMC) was studied using three estrogen-receptor (ER)-positive (MCF-7, R-27, and Br-10) and one ER-negative (MX-1) human breast carcinoma xenograft serially transplanted into nude mice, and the effect of estradiol (E2) priming on the ant