Antitumor activity and immunomodulatory effects of the intraperitoneal administration of Kanglaite in vivo in Lewis lung carcinoma
β Scribed by Pei Pan; Yan Wu; Zhu-Ying Guo; Rong Wang; Yu-Jie Wang; Yong-Fang Yuan
- Book ID
- 119295458
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 389 KB
- Volume
- 143
- Category
- Article
- ISSN
- 0378-8741
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Two BCG vaccine preparations were prepared following different production methods. Immuno-BCG Pasteur F was produced by surface culture on Sauton medium; BCG-R1V was a homogenous stirred deep culture. The antitumor effects of the two BCG vaccines were investigated on the Lewis lung carcinoma (3LL)
## Abstract Gene transfer of Fas ligand (FasL) to tumor cells has been demonstrated to inhibit tumor growth __in vivo__, and neutrophils are primarily responsible for this immunoprotection. The granulocyteβmacrophage colony stimulating factor (GMβCSF) secreted by tumor vaccine can recruit dendritic