✦ LIBER ✦

Antitumor activity and biochemistry of novel analogs of the antibiotic, CC-1065

✍ Scribed by W. Wierenga; B.K. Bhuyan; R.C. Kelly; W.C. Krueger; L.H. Li; J.P. McGovren; D.H. Swenson; M.A. Warpehoski

Book ID: 118372050
Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 674 KB
Volume: 25
Category: Article
ISSN: 0065-2571
DOI: 10.1016/0065-2571(86)90012-9

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Genotoxicity of the antitumor antibiotic

Genotoxicity of the antitumor antibiotic CC-1065

✍ Harbach, P.R.; Trzos, R.J.; Mazurek, J.H.; Zimmer, D.M.; Petzold, G.L.; Bhuyan, 📂 Article 📅 1986 🏛 Oxford University Press 🌐 English ⚖ 359 KB

Efficient Synthesis of the Pharmacophore

Efficient Synthesis of the Pharmacophore of the Highly Potent Antitumor Antibiotic CC-1065

✍ Lutz F. Tietze; Wilm Buhr; Jan Looft; Thomas Grote 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB

Synthesis of Ring Size seco-Analogs of t

Synthesis of Ring Size seco-Analogs of the Antitumor Antibiotic CC-1065 by Two Consecutive Transition Metal-Initiated Transformations

✍ Lutz F. Tietze; Jan Looft; Tim Feuerstein 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB

Coupling of cyclopropapyrroloindole (CPI

Coupling of cyclopropapyrroloindole (CPI) derivatives. The preparation of CC-1065, ent-CC-1065, and analogs

✍ Kelly, Robert C.; Gebhard, Ilse; Wicnienski, Nancy; Aristoff, Paul A.; Johnson, 📂 Article 📅 1987 🏛 American Chemical Society 🌐 English ⚖ 270 KB

Synthesis and antitumor activity of anal

Synthesis and antitumor activity of analogs of the antitumor antibiotic chartreusin

✍ Takai, Makoto; Uehara, Yoshimasa; Beisler, John A. 📂 Article 📅 1980 🏛 American Chemical Society 🌐 English ⚖ 770 KB

Adozelesin, a selected lead among cyclop

Adozelesin, a selected lead among cyclopropylpyrroloindole analogs of the DNA-binding antibiotic, CC-1065

✍ Li H. Li; Robert C. Kelly; Martha A. Warpehoski; J. Patrick McGovren; Ilse Gebha 📂 Article 📅 1991 🏛 Springer US 🌐 English ⚖ 854 KB

Adozelesin (U-73975) is a potent synthetic cyclopropylpyrroloindole (CPI) analog of the cytotoxic DNAbinding antibiotic, CC-1065. In contrast to the natural product, adozelesin and related CPI analogs do not cause delayed death in non-tumored mice. Adozelesin, selected from a series of analogs for i