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Antitrypanosomal structure–activity-relationship study of synthetic cynaropicrin derivatives

✍ Scribed by Usuki, Toyonobu; Sato, Makiko; Hara, Shihori; Yoshimoto, Yukiko; Kondo, Ryosuke; Zimmermann, Stefanie; Kaiser, Marcel; Brun, Reto; Hamburger, Matthias; Adams, Michael

Book ID
122329108
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
358 KB
Volume
24
Category
Article
ISSN
0960-894X

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## Abstract This work is part of a plan to investigate the structure–bitterness relationship in sesquiterpene lactones of dietary origin. The major guaianolides from artichoke (__Cynara scolimus__ L) were chosen for this study because of their exceedingly bitter taste and well‐proven safety at conc