Antithrombotic effects of YM466, a synth
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Yoshiyuki Iwatsuki; Seiji Kaku; Yumiko Moritani; Yuta Taniuchi; Fukushi Hirayama
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Article
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2003
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John Wiley and Sons
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English
β 88 KB
## Abstract The antithrombotic effects of YM466, a synthetic direct inhibitor of human factor Xa (FXa), were evaluated in an arterioβvenous shunt thrombosis model in squirrel monkeys. YM466 significantly inhibited thrombus formation after continuous IV zx infusion at doses of 3β30 Β΅g/kg/h. Although