Antithrombotic effects in a rat model of aspirin-insensitive arterial thrombosis of desethyl KBT-3022, the main active metabolite of a new antiplatelet agent, KBT-3022

Antithrombotic effects of KBT-3022, a no

Antithrombotic effects of KBT-3022, a novel antiplatelet agent, in an arterial thrombosis model in the guinea-pig

✍ Masamitsu Shimazawa; Yoshiharu Takiguchi; Kazuo Umemura; Mitsuyoshi Nakashima 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 171 KB 👁 2 views

We examined the antithrombotic effect of KBT-3022, a novel antiplatelet agent, on photochemically induced arterial thrombosis in the guinea-pig saphenous artery, and compared its effect with that of aspirin and that of ticlopidine. Pretreatment with KBT-3022 [0.1 mg (0.2 µmole), 0.3 mg (0.7 µmole),