Antispermatogenic effect of chromatographic fractions isolated from petroleum ether extract of Mentha arvensis leaf in the albino mouse
✍ Scribed by Nidhi Sharma; Dennis Jacob
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 102 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0951-418X
No coin nor oath required. For personal study only.
✦ Synopsis
The antifertility activity of column chromatographically isolated fractions (petroleum ether:benzene 1:1 v/v and chloroform:methanol 1:1 v/v) of a petroleum ether extract of Mentha arvensis leaf were evaluated in the male albino mouse. Administration of the fractions for 20 days at a dose of 1.0 mg/mouse/alternate day reduced the wet weights of genital organs and induced infertility in the male mouse without loss of libido as evaluated by sterile matings with normal proestrus females. Absence of spermatozoa in the cauda epididymes as a consequence of spermatogenic arrest is considered contributory to the antifertility effect.