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Antispasmodic effect of 4′-methylepigallocatechin on guinea pig ileum

✍ Scribed by Marcelly Barbosa da Rocha; Fábia Valéria Menezes Souza; Charlez dos Santos Estevam; Cosimo Pizza; Antônio Euzébio Goulart Sant'ana; Rosilene Moretti Marçal

Book ID
118446082
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
354 KB
Volume
83
Category
Article
ISSN
0367-326X

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✍ M. E. Arzate; H. Ponce; Herminia Pasantes-Morales 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 518 KB

The effects of 4-aminopyridine (4-AP) and of taurine on the guinea pig ileum were examined. Four-AP increases the basal activity from 1.3 to 6.45 cm2/min. This effect is atropine-sensitive and calcium-dependent. Taurine counteracts the effects of 4-AP on muscle contracture in a concentration-depende