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Antisense targeting human papillomavirus type 16 E6 and E7 genes contributes to apoptosis and senescence in SiHa cervical carcinoma cells

✍ Scribed by Ni Sima; Shixuan Wang; Wei Wang; Debo Kong; Qian Xu; Xu Tian; Aiyue Luo; Jianfeng Zhou; Gang Xu; Li Meng; Yunping Lu; Ding Ma

Book ID
113961117
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
352 KB
Volume
106
Category
Article
ISSN
0090-8258

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Certain human papillomaviruses (HPV), mainly types 16 and 18, have been widely recognized as an essential etiologic factor for the development of carcinoma of the uterine cervix. The early HPV proteins E6 and E7 are consistently expressed in the tumor cells, and cervical-carcinoma patients can devel