Transfection of ฮฑ(1,3)fucosyltransferase
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Kara M. Hiller; John P. Mayben; Katharine M. Bendt; George A. Manousos; Kate Sen
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Article
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2000
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John Wiley and Sons
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English
โ 185 KB
Sialyl Lewis x and sialyl Lewis a are oncodevelopmental antigens involved in the pathogenesis of colon adenocarcinoma. Biosynthesis of these glycans is controlled by a(1,3/1,4)fucosyltransferases. We report the disruption of sialyl Lewis x/a biosynthesis and inhibition of colon carcinoma cell prolif