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Antisense Oligonucleotides Specific to Mutated K-ras Genes Inhibit Invasiveness of Human Pancreatic Cancer Cell Lines

โœ Scribed by Nakada, Yuji; Saito, Seiji; Ohzawa, Kouji; Morioka, Cintia Yoko; Kita, Kei-ichiro; Minemura, Masami; Takahara, Terumi; Watanabe, Akiharu


Book ID
123450155
Publisher
S. Karger AG
Year
2001
Tongue
English
Weight
235 KB
Volume
1
Category
Article
ISSN
1424-3903

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Growth inhibition of human pancreatic ca
โœ Kei-ichiro Kita; Seiji Saito,; Cintia Y. Morioka; Akiharu Watanabe ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 129 KB ๐Ÿ‘ 2 views

About 90% of human pancreatic cancers carry K-ras point mutation, which may play an important role in tumorigenesis. We investigated the inhibitory effects of anti-sense oligonucleotides targeting K-ras point mutation on the growth of cultured human pancreatic cancer cells. Eight human pancreatic ca