This state-of-the-art reference provides comprehensive coverage of the development of antisense oligonucleotides to inhibit cancer cells as well as those involved in infectious, inflammatory, and immune-mediated diseases-highlighting new tools and technologies in medicinal chemistry, RNA biochemistr
Antisense Drug Technology: Principles, Strategies and Applications
โ Scribed by Stanley T. Crooke
- Publisher
- CRC Press
- Year
- 2007
- Tongue
- English
- Leaves
- 45
- Edition
- 2
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Synopsis
Offering contributions from over 60 experts, this volume provides comprehensive coverage of the development of antisense oligonucleotides and showcases the benefits of antisense drugs-including reduced toxicity and earlier disease detection-useful for treating cancer, as well as infectious, inflammatory, and immune-mediated diseases. It presents previously unpublished data on the use of antisense technology to dissect pharmacological processes and confirm the roles of various genes, and highlights advances in chemistry, RNA biochemistry, and molecular and cellular biology leading to new therapeutic compounds. The text is augmented with numerous tables, illustrations, and a wealth references.
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