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Antisem to carcinoembryonic antigen recognizes a phosphotyrosine-containing protein in human colon cancer cell lines

✍ Scribed by Keith M. Skubitz; Thomas P. Ducker; Amy P.M. Skubitz; Said A. Goueli

Book ID
115927224
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
727 KB
Volume
318
Category
Article
ISSN
0014-5793

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A bispecific monoclonal antibody (BsMAb) recognising carcinoembryonic antigen (CEA) and doxorubicin (Dox) was used in colorimetric microcytotoxicity assays with 3 human colon cancer cell lines (COLO320DM, SKCO1 and LS174T) showing no, high or medium CEA expression, respectively. The IC50 values for