The likelihood of a sustained response to a course of interferon in patients with chronic hepatitis C correlates with several clinical and viral factors, including age, viral genotype and initial levels of hepatitis C virus (HCV) RNA in serum. The role of race and ethnicity has not been assessed. We
Antipyrine clearance and response to interferon therapy in chronic hepatitis
β Scribed by A Fabbri; G P Bianchi; G Marchesini
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 212 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
β¦ Synopsis
In a recent publication by Panzar et al., 1 the authors have 55. used 400-to 1,000-d polyethylene glycol to study small intes-4. Lake JR, Licko V, van Dyke RN, Scharschmidt BF. Biliary secretion of fluid-markers by the isolated perfused rat liver. J Clin Invest 1985;76:676-tinal absorption in portacaval-shunted rats. The results are 684.
interesting, but we want to draw the attention to some of 5. Friman S, Ra Λdberg G, Svanvik J. Hepatic clearance of polyethylene glycol the conclusions made by the authors. In this study, a higher 900 and mannitol in the pig. Digestion 1988;
π SIMILAR VOLUMES
## Predictors of a Sustained Beneficial Response to Interferon Alfa Therapy in Chronic Hepatitis C Interferon alfa was first reported to have beneficial effects in chronic hepatitis C in the mid-l980s,' effects that were subsequently verified in multiple randomized controlled trials performed in
CORRESPONDENCE 1287 tive anions determine the potential for crystal precipi-though the location within the stone is not identified. Thus, their data would seem to confirm our findings tation within bile. Certain disease states predispose and be in conflict with the statement in their letter to supe
Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes (CTL) have been shown to play a role in host defense and pathogenesis of chronic HCV infection. Our aim was to test the hypothesis that intrahepatic HCV-specific CTL activity may impact subsequent response to interferon alfa (IFN-β£) therapy. O
Group 1. Two hundred eleven patients with chronic hepatitis C