Antipsychotics with different D2 dopamine receptor potency affect differently the postsynaptic density protein homer at glutamatergic metabotropic synapse

Neuroleptics with differential affinitie

Neuroleptics with differential affinities at dopamine D2 receptors and sigma receptors affect differently the N-methyl-D-aspartate-induced increase in intracellular calcium concentration: Involvement of protein kinase

✍ Teruo Hayashi; Tsung-Ping Su; Ariyuki Kagaya; Akira Nishida; Masami Shimizu; Shi 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB 👁 2 views

This study examined the effect of chronic antipsychotic treatment on the NMDA-elicited changes in intracellular free Ca2+ concentration ([Ca2+]i) in the primary culture of rat frontal cortical neurons. Antipsychotics used in the study were chosen for their differential affinities at dopamine D2 rece