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Antipsychotic efficacy and good tolerability in a Phase III placebo-controlled study of pimavanserin in patients with Parkinson's disease psychosis (ACP-103-020)

✍ Scribed by Ballard, Clive; Mills, Roger; Williams, Hilde; Chi-Burris, Kathy; Bahr, Daun; Cummings, Jeffrey


Book ID
122763989
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
54 KB
Volume
9
Category
Article
ISSN
1552-5260

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## Abstract Piribedil is a non‐ergot D2/D3 agonist with a significant antagonist action on Ξ±2A and Ξ±2C adrenergic receptor subtypes. This double‐blind placebo‐controlled study was undertaken to confirm the efficacy of 150 mg/day piribedil po in improving motor symptoms of idiopathic Parkinson's dis