Antipsychotic Drugs Inhibit the Function of Breast Cancer Resistance Protein
✍ Scribed by Jun-Sheng Wang; Hao-Jie Zhu; John S. Markowitz; Jennifer L. Donovan; Hong-Jie Yuan; C. Lindsay DeVane
- Book ID
- 111316554
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 334 KB
- Volume
- 103
- Category
- Article
- ISSN
- 1742-7835
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## Abstract Breast cancer resistance protein (BCRP) is a half‐molecule ABC transporter highly expressed in mitoxantrone‐resistant cells. In our study we established PA317 transfectants expressing Myc‐tagged BCRP (MycBCRP) or HA‐tagged BCRP (HABCRP). The exogenous BCRP protein migrated as a 70‐kDa p