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Antipsychotic drugs clozapine and olanzapine upregulate bcl-2 mRNA and protein in rat frontal cortex and hippocampus

โœ Scribed by Ou Bai; Honghong Zhang; Xin-Min Li


Book ID
113499603
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
831 KB
Volume
1010
Category
Article
ISSN
0006-8993

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## Abstract Antipsychotic (neuroleptic) drugs induce structural alterations in synaptic terminals and changes in the expression of presynaptic protein genes. Whether there are also changes in corresponding postsynaptic (dendritic) markers has not been determined. We describe the effect of 14โ€day tr