Synthesis and evaluation of oryzalin ana
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Molla M. Endeshaw; Catherine Li; Jessica de Leon; Ni Yao; Kirk Latibeaudiere; Ko
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Article
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2010
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Elsevier Science
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English
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The synthesis and evaluation of 20 dinitroanilines and related compounds against the obligate intracellular parasite Toxoplasma gondii is reported. Using in vitro cultures of parasites in human fibroblasts, we determined that most of these compounds selectively disrupted Toxoplasma microtubules, and