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Antiproliferative effects of c-myc antisense oligonucleotide in prostate cancer cells: A novel therapy in prostate cancer

✍ Scribed by K.C. Balaji; Hari Koul; Sankar Mitra; Carlos Maramag; Premveer Reddy; Mani Menon; Rajwant Kaur Malhotra; Seethalaksmi Laxmanan

Book ID
119486977
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
935 KB
Volume
50
Category
Article
ISSN
0090-4295

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Antiproliferative effects of AVN944, a n
Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells
✍ Daniel Floryk; Timothy C. Thompson πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 French βš– 384 KB

## Abstract Inosine 5‐monophosphate dehydrogenase II, a key enzyme in the __de novo__ synthesis of purine nucleotides, is expressed in prostate tumors and prostate cancer cells. AVN944 is a new, specific, noncompetitive IMPDH inhibitor. In this study, we investigated the effects of IMPDH inhibitor