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Antiproliferative Effect of Baylis—Hillman Adducts and a New Phthalide Derivative on Human Tumor Cell Lines.

✍ Scribed by Luciana K. Kohn; C. H. Pavam; D. Veronese; F. Coelho; J. E. De Carvalho; Wanda P. Almeida


Publisher
John Wiley and Sons
Year
2006
Weight
21 KB
Volume
37
Category
Article
ISSN
0931-7597

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We examined the effect of loss of wild type TP53 activity on the chromosomal stability of a human colonic adenoma derived cell line (designated AA/C1) by studying transfected variants which express different TP53 mutations. Using gross chromosomal aberrations as a measure of instability, we studied