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Antiproliferative effect of 1,25-dihydroxyvitamin D3 and its analogs on human colon adenocarcinoma cells (CaCo-2): Influence of extracellular calcium

✍ Scribed by Heide S. Cross; Christine Huber; Meinrad Peterlik


Book ID
115764220
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
428 KB
Volume
179
Category
Article
ISSN
0006-291X

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Effects of 1Ξ±,25(OH)2D3 and its analogs
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## Abstract 1Ξ±,25‐Dihydroxyvitamin D~3~ (1Ξ±,25(OH)~2~D~3~) and non‐calcemic vitamin D analogs induce a persistent state of immaturity in dendritic cells both in vitro and in vivo. These effects are transcriptional in nature, involve alterations in surface ligands as well as cytokine synthesis and r