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Antiproliferative and antiangiogenic effects of 3-methylcholanthrene, an aryl-hydrocarbon receptor agonist, in human umbilical vascular endothelial cells

✍ Scribed by Shu-Hui Juan; Ja-Ling Lee; Pei-Yin Ho; Yi-Hsuan Lee; Wen-Sen Lee

Book ID: 113585810
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 458 KB
Volume: 530
Category: Article
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2005.11.023

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## Abstract We previously reported that 3‐methylcholanthrene (3MC), an aryl‐hydrocarbon receptor (AhR) agonist, inhibits the proliferation of human umbilical vascular endothelial cells (HUVECs; Juan et al., 2006, Eur J Pharmacol 530: 1–8). Herein, pretreatment of HUVECs with p21 or p27 small interf

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