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Antiproliferative activity of retinoids, interferon α and their combination in five human transformed cell lines

✍ Scribed by Frey, J.R.; Peck, R.; Bollag, W.

Book ID: 121992028
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 480 KB
Volume: 57
Category: Article
ISSN: 0304-3835
DOI: 10.1016/0304-3835(91)90161-A

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Retinoids modulate several cell functions and especially inhibit the growth of a wide variety of cells including breast cancer. Retinoic acid receptor-gamma (RAR-gamma) has been shown to mediate the antiproliferative activity of retinoids. To further test this hypothesis we examined the effects of d