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Antioxidants prevent the cytotoxicity of manganese in RBE4 cells

✍ Scribed by A.P. Marreilha dos Santos; Dinamene Santos; Catherine Au; Dejan Milatovic; Michael Aschner; M. Camila C. Batoréu

Book ID
113503752
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
653 KB
Volume
1236
Category
Article
ISSN
0006-8993

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## Abstract Manganese (Mn), an essential nutrient, is neurotoxic at high levels and has been associated with the development of a parkinsonian syndrome termed __manganism__. Currently, the mechanisms responsible for transporting Mn across the blood–brain barrier (BBB) are unknown. By using rat brai