Antioxidant therapy and ischemia-reperfusion injury
β Scribed by D.Neil Granger
- Book ID
- 113385331
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 128 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0891-5849
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The purpose of this study was to investigate the effectiveness of superoxide dismutase (SOD) overexpression in an acute model of hepatic oxidative stress. Oxidative stress was established using a warm ischemia-reperfusion model, where nearly 70% of the liver was made hypoxic by clamping the hepatic
Oxidative stress is an important factor in many pathological conditions such as inflammation, cancer, ageing and organ response to ischemia-reperfusion. Humans have developed a complex antioxidant system to eliminate or attenuate oxidative stress. Liver ischemia-reperfusion injury occurs in a number