✦ LIBER ✦

Antioxidant function of metallothioneins

✍ Scribed by Kelley Kiningham; Edward Kasarskis

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 50 KB
Volume: 11
Category: Article
ISSN: 0896-548X
DOI: 10.1002/(sici)1520-670x(1998)11:2/3<219::aid-jtra12>3.0.co;2-u

No coin nor oath required. For personal study only.

✦ Synopsis

Since the discovery of metallothionein in 1957, it has been accepted that the primary roles of this protein are: 1) detoxification of heavy metals, and 2) regulation of the metabolism of essential metals. Recently, studies have suggested an additional role for metallothionein as a free radical scavenger. This article reviews in vitro and in vivo evidence which supports the role for metallothionein in modulation of reactive oxygen species.

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