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Antioxidant activity of methimazole–copper(II) bioactive species and spectroscopic investigations on the mechanism of its interaction with Bovine Serum Albumin

✍ Scribed by Nora M. Urquiza; Luciana G. Naso; Silvia G. Manca; Luis Lezama; Teófilo Rojo; Patricia A.M. Williams; Evelina G. Ferrer


Book ID
113856698
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
996 KB
Volume
31
Category
Article
ISSN
0277-5387

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The potential binding interaction(s) of the anti-thyroid drug methimazole (MMZ) with the protein bovine serum albumin (BSA) has been studied using isothermal titration calorimetry (ITC) and UV-Visible, fluorescence and circular dichroism (CD) spectroscopic techniques. The binding of MMZ to BSA has b