Antioxidant Activity of a Dihydroquercetin Isolated from Larix gmelinii (Rupr.) Rupr. Wood
✍ Scribed by V. K. Kolhir; V. A. Bykov; A. I. Baginskaja; S. Y. Sokolov; N. G. Glazova; T. E. Leskova; G. S. Sakovich; N. A. Tjukavkina; Yu. A. Kolesnik; I. A. Rulenko
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 401 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0951-418X
No coin nor oath required. For personal study only.
✦ Synopsis
We have demonstrated that dihydroquercetin is an antioxidant and possesses the properties of protecting capillaries, which is consistent with its action as an antiinflammatory agent, gastro-and hepatoprotecting agent, and its diuretic and hypolipidaemic activity. As a capillary protector, dihydroquercetin is 3.4 times more effective at a dose of l0Omgkg and 4.9 times at a dose of 30Omgkg than the well known bioflavonoid, quercetin. Dihydroquercetin shows a dose dependent suppression of lipid peroxidation in the rat liver. The hypolipidaemic activity of dihydroquercetin at 250 mgkg is comparable to that of polysponin.