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Antimutagenicity of cinnamaldehyde and vanillin in human cells: Global gene expression and possible role of DNA damage and repair

✍ Scribed by Audrey A. King; Daniel T. Shaughnessy; Kanae Mure; Joanna Leszczynska; William O. Ward; David M. Umbach; Zongli Xu; Danica Ducharme; Jack A. Taylor; David M. DeMarini; Catherine B. Klein

Book ID: 113808970
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 345 KB
Volume: 616
Category: Article
ISSN: 0027-5107
DOI: 10.1016/j.mrfmmm.2006.11.022

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## Abstract The human protein MED1, also known as MBD4, was isolated in a yeast two‐hybrid screening as an interactor of the mismatch repair protein MLH1. MED1 contains an N‐terminal 5‐methylcytosine binding domain (MBD), which allows binding to methylated DNA, and a C‐terminal catalytic domain wit