Quere ´taro, Qro., Me ´xico Carotenoids (carotenes and xanthophylls) are ex-AFB 1 mutagenicity than pure lutein. The percentcellent antioxidants with antimutagenic and anticar-ages of inhibition on AFB 1 mutagenicity were 37, cinogenic properties. They occur naturally in some 66, and 76% for lutein, oleoresin, and xanthophyll foods such as carrots, red tomatoes, butter, cheese, plus at the dose of 2 mg/plate, respectively. Lutein paprika, palm oil, corn kernels, Marigold petals, had a modest effect on the DNA-repair system of annatto, and red salmon. In the present study, we YG1024. In spectrophotometric studies, a new abused the Salmonella plate incorporation test to ex-sorption peak was detected at 378 nm when lutein amine the effect of xanthophylls extracted from and AFB 1 were incubated together, and lutein re-Aztec Marigold (Tagetes erecta) on the AFB 1 muta-acted with AFB 1 metabolites. The results suggest that genicity, using tester strain YG1024. The effect of the inhibitory mechanism of lutein against AFB 1 mulutein on the DNA-repair system in YG1024 was tagenicity is most probably the result of a combinainvestigated by a pre-incubation test. In a dose-re-tion of the following events: formation of a complex sponse curve of AFB 1 , the mutagenic potency was between lutein and AFB 1 , direct interaction be-1,031 revertants/nmol. The dose of 0.5 mg AFB 1 / tween lutein and AFB 1 metabolites, and finally that plate was chosen for the antimutagenicity studies. the lutein may also affect the metabolic activation Pure lutein and xanthophylls from Aztec Marigold of AFB 1 by S9 and the expression of AFB 1 -modified flower (oleoresin and xanthophyll plus) inhibited the Salmonella DNA.