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Antimitochondrial autoantibodies of primary biliary cirrhosis as a novel probe in the study of 2-oxo acid dehydrogenases in patients with mitochondrial myopathies

✍ Scribed by Herawati Sudoyo; Sangkot Marzuki; Ian Trounce; Edward Byrne


Book ID
118931092
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
674 KB
Volume
98
Category
Article
ISSN
0022-510X

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Autoantibodies against inner mitochondrial membrane proteins are a hallmark of primary biliary cirrhosis. Specifically, these antimitochondrial autoantibodies recognize two polypeptides of approximately 70 and 52 kD, respectively. Although the specificity of antimitochondrial autoantibodies has been