Antimicrobial Resistance: Global Challenges and Future Interventions

✍ Scribed by Sabu Thomas

• Publisher: Springer Singapore;Springer
• Year: 2020
• Tongue: English
• Leaves: 236
• Edition: 1st ed.
• Category: Library

✦ Synopsis

Antimicrobial resistance is a major global public health problem. This book focuses on the clinical implications of multi-drug resistant pathogens; tracking AMR and its evolutionary significance; antifungal resistance; and current and alternative treatment strategies for AMR, including antivirulent, antibiofilm and antimicrobial resistance breakers, repurposing of drugs, and probiotic therapy. Advances in antimicrobial stewardship, antibiotic policies from a global perspective and their impacts are also discussed. The book also explores the use of omics approaches to gain insights into antibacterial resistance, and includes chapters on the potential benefits of a ‘One Health approach’ describing the environmental and zoonotic sources of resistant genes and their effects on the global resistance pool.

✦ Table of Contents

Front Matter ....Pages i-xiii
The Evolution of Microbial Defence Systems Against Antimicrobial Agents (Archana Madhav, Robert C. Will, Ankur Mutreja)....Pages 1-31
Carbapenem Resistance in Gram-Negative Bacilli: Mechanisms and Challenges (Sarita Mohapatra, Arti Kapil)....Pages 33-52
Influence of Antimicrobials on the Gut Microbiota (Goutam Chowdhury, T. Ramamurthy)....Pages 53-79
Influence of Abiotic Factors in the Emergence of Antibiotic Resistance (Sanjucta Dutta, T. Ramamurthy)....Pages 81-100
Polluted Coastal and Estuarine Environments: A Potential Reservoir for AMR Determinants in Various Pathogenic Bacteria (A. A. Mohamed Hatha, Puthenkandathil Sukumaran Divya, Silvester Reshma, John Nifty)....Pages 101-134
AMR in Animal Health: Issues and One Health Solutions for LMICs (Robin J. Paul, Digna Varghese)....Pages 135-149
Antifungal Resistance: Current Concepts (Gagandeep Singh, Immaculata Xess)....Pages 151-163
“Planetary Health” Perspectives and Alternative Approaches to Tackle the AMR Challenge (Padma Venkatasubramanian, S. P. Balasubramani, Rajan Patil)....Pages 165-188
Use of Bacterial Cell Wall Recycle Inhibitors to Combat Antimicrobial Resistance (Ramya Raghavan, Jharna Mandal)....Pages 189-206
Status Quo of Omics Technologies in Analyzing the Genetic Mediators of Antimicrobial Resistance at Sub-MIC Concentrations (Merin Paul, Vidhyalakshmi Mohan, Lekshmi Narendrakumar, Iype Joseph, Sabu Thomas)....Pages 207-230
Correction to: Carbapenem Resistance in Gram-Negative Bacilli: Mechanisms and Challenges (Sarita Mohapatra, Arti Kapil)....Pages C1-C1

✦ Subjects

Biomedicine; Pharmaceutical Sciences/Technology; Pharmacoeconomics and Health Outcomes; Drug Resistance; Applied Microbiology