โ Scribed by Prof. David A. Phoenix, Dr. Sarah R. Dennison, Dr. Frederick Harris(auth.)
No coin nor oath required. For personal study only.
In this didactically-written text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers.
The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application by discussing their design principles, target membranes and structure-activity relationships. The final part of the book describes recent successes in the application of peptides as anticancer agents.Content:
Chapter 1 Antimicrobial Peptides: Their History, Evolution, and Functional Promiscuity (pages 1โ37):
Chapter 2 Cationic Antimicrobial Peptides (pages 39โ81):
Chapter 3 Anionic Antimicrobial Peptides (pages 83โ113):
Chapter 4 Graphical Techniques to Visualize the Amphiphilic Structures of Antimicrobial Peptides (pages 115โ144):
Chapter 5 Models for the Membrane Interactions of Antimicrobial Peptides (pages 145โ180):
Chapter 6 Selectivity and Toxicity of Oncolytic Antimicrobial Peptides (pages 181โ221):
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