## Abstract 3(2‐pyridinylmethylene)‐5‐aryl‐2(3__H__)‐furanones and 3(3‐pyridinylmethylene)‐5‐aryl‐2(3__H__)‐furanones were prepared as a mixture of (E) and (Z) stereoisomers by condensing pyridine‐2‐carboxaldehyde and pyridine‐3‐carboxaldehyde with 3‐aroylpropionic acids. The reaction of the furano
Antimicrobial activity of 5-alkyl-3H-furanones and their sulfur analogs
✍ Scribed by N. A. Morozova; V. A. Sedavkina; A. Yu. Egorova; N. N. Sorokin; L. K. Kulikova
- Book ID
- 112400264
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 202 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0091-150X
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A synthesis of ethyl-, butyl-, hexyl-and dodecyi-substituted fimbrolides from aikyl-substituted levulinic acid derivatives through brominafiou and acid promoted lactonisafion is described. The underlying reactions have been investigated using levulinic acid as a model, and the effects of varying the
Easily available 3,4-dibromo-2(5H)-furanone undergoes a regioselective cross-coupling reaction with alkylboronic acids in the presence of catalytic amounts of PdCl2(MeCN)2 and AsPh3 and a large molar excess of Ag2O to provide the corresponding 4-alkyl-3-bromo-2(5H)-furanones in satisfactory yields.