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Antimalarial chemotherapeutic peroxides: artemisinin, yingzhaosu A and related compounds

✍ Scribed by Kristina Borstnik; Ik-hyeon Paik; Theresa A Shapiro; Gary H Posner


Book ID
114043433
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
136 KB
Volume
32
Category
Article
ISSN
0020-7519

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Synthesis, Structure, and Antimalarial A
✍ Charles W. Jefford; Javier A. Velarde; GΓ©rald Bernardinelli; Dorothy H. Bray; Da πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 German βš– 831 KB

Two sets of tricyclic 1,2,4-trioxanes containing the ABC (10, 11) and ACD ring portions (21, 22, 32, 33, 37, and 38) of artemisinin (1) were synthesized by successive photo-oxygenation of appropriate enol-ether precursors to 1,2-dioxanes and inter-and intramolecular reaction with a carbonyl compound