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Antimalarial Activity of Pyrroloiminoquinones from the Australian Marine Sponge Zyzzya sp.

✍ Scribed by Davis, Rohan A.; Buchanan, Malcolm S.; Duffy, Sandra; Avery, Vicky M.; Charman, Susan A.; Charman, William N.; White, Karen L.; Shackleford, David M.; Edstein, Michael D.; Andrews, Katherine T.; Camp, David; Quinn, Ronald J.


Book ID
111892123
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
569 KB
Volume
55
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Isolation and Antit
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(+)-7-Bromotrypargine: an antimalarial Ξ²
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Mass-directed isolation of the CH 2 Cl 2 /MeOH extract from the Australian marine sponge Ancorina sp. resulted in the purification of a new antimalarial b-carboline, (+)-7-bromotrypargine 1, along with the previously isolated natural product, 6-bromotryptamine 2. The structure of 1 is determined by