𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Antileishmanial Chalcones: Statistical Design, Synthesis, and Three-Dimensional Quantitative Structure−Activity Relationship Analysis

✍ Scribed by Nielsen, Simon Feldbæk; Christensen, Søren Brøgger; Cruciani, Gabriele; Kharazmi, Arsalan; Liljefors, Tommy

Book ID
120448141
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
207 KB
Volume
41
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Three-Dimensional Quantitative Structure
Three-Dimensional Quantitative Structure Activity Relationship for Cyp2d6 Substrates
✍ Snyder, Richard ;Sangar, Rajesh ;Wang, Jibo ;Ekins, Sean 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 377 KB

Without a crystallized structure for a human cytochrome P450, the use of computational molecular modeling is one approach to examine the active site requirements of substrate and inhibitor specificity. CYP2D6 is undoubtedly the most studied polymorphic human CYP and it is therefore desirable for dru