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Antileishmanial activity of the ether phospholipid ilmofosine

โœ Scribed by S.L. Croft; R.A. Neal; E.A. Thornton; D.B.J. Herrmann


Book ID
107850526
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
361 KB
Volume
87
Category
Article
ISSN
0035-9203

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A series of new 2-[3-(2-alkyloxy-ethyl)-adamantan-1-yl]-ethoxy substituted ether phospholipids was synthesized and their antileishmanial activity was evaluated against Leishmania infantum amastigotes. The majority of the new analogues were significantly less cytotoxic than miltefosine while, antipar