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Antihypertensive and monoamine oxidase inhibitory activity of 3-amino-2-oxazolidinone (3AO) and its condensation product with 2-substituted-3-formyl-4-oxo-(4H) pyrido(l,2-a)pyrimidines

✍ Scribed by C.L. Kaul; R.S. Grewal


Book ID
115771381
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
820 KB
Volume
21
Category
Article
ISSN
0006-2952

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Reaction of 2-substituted-4-oxo-4H-pyrid
✍ Masashi Shirai; Hidekazu Kuwabara; Satoshi Matsumoto; Hidetoshi Yamamoto; Akikaz πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 282 KB

A facile oxime-nitrone isomerization through the 1,2-hydrogen shift in 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde oximes is discussed. The resultant NH-nitrones are trapped by maleimides to afford intermolecular cycloadducts. The reaction of the oximes with electron-deficient acetylenes undergo